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Ratings are based on information from literature reviews, original studies, and material safety data sheets. Complex mixtures are given the highest ranking of any ingredient for reproductive hazard, regardless of percent composition. General toxicity rankings for mixtures are based on actual test data or, where data are lacking, are estimates based on knowledge of the composition and toxicity of the ingredients. These rankings are subject to change if new information substantially changes the understanding of the toxic effects of any substance. All classifications are guidelines, not rigid rules. Certain individuals may be more or less sensitive to any chemical, or may react in ways not previously known.
| 0 | NO APPRECIABLE HAZARD |
| 1 | MAY CAUSE REVERSIBLE EFFECTS GENERALLY NOT LIFE-THREATENING |
| 2 | MAY CAUSE IRREVERSIBLE EFFECTS GENERALLY NOT LIFE-THREATENING |
| 3 | MAY CAUSE IRREVERSIBLE EFFECTS WHICH CAN BE LIFE-THREATENING |
| U | UNKNOWN OR INSUFFICIENT INFORMATION TO IDENTIFY |
| X | SIMPLE ASPHYXIANT |
| A+ | HUMAN REPRODUCTIVE HAZARD WITH NO KNOWN NO-EFFECT DOSE |
| A | HUMAN REPRODUCTIVE HAZARD WITH KNOWN NO-EFFECT DOSE |
| A- | UNCONFIRMED HUMAN REPRODUCTIVE HAZARD |
| B+ | MULTIPLE REPRODUCTIVE EFFECTS IN ANIMALS BUT NO HUMAN DATA |
| B | MIXED REPRODUCTIVE EFFECTS IN ANIMALS BUT NO HUMAN DATA |
| B- | FEW REPRODUCTIVE EFFECTS IN ANIMALS BUT NO HUMAN DATA |
| C | NO REPRODUCTIVE DATA FOUND |
| D | INSUFFICIENT INFORMATION TO IDENTIFY |
| E | KNOWN NOT TO AFFECT ANIMAL REPRODUCTION BUT NO HUMAN DATA |
| F | KNOWN NOT TO AFFECT HUMAN REPRODUCTION |